[Sirrotica]

With log manifolds and 2 bolt flanges 2 1/4" is usually about as big as you can go.

The RA manifolds have larger flange areas enabling 2 1/2" if you enlarge the center hole in the flange.

There is a way to adapt up to 3" pipes using header collector flanges adapted to the 2 or 3 hole flanges, requires welding and fab skills. Basically the old flange pattern is used to build a plate that is first bolted to the manifold and then has the 3 hole header collector flange pattern on the 3 inch pipe that is then bolted to the adapter plate.

Way back years ago, on the 67 GTO in my middle signature picture I built adapters to adapt the 3 hole Pontiac RA head pipes to driveshaft tubing (3 1/2 inch OD) that dumped at the rear axle. The seat of the pants dyno was feeling the improvement...LOL