Upon my intial fire up of the new 428+ w/ hyd roller (Crane lifters), Ray & myself had similar problem. It would only fire on one cylinder? Having assembeled the lifters as per the Crane instructions; we did not pump them up and installed them dry, adjusting lash. Did prime the engine untill oil flowed through all roller rockers, oil lines, etc...
We called everyone, Dude included, couldn't figure it out? W/ Ken and a couple of other's help we finally figured out that the valves weren't closing due to the lifter's adj. being off from actually pumping up and not allowing them to close!!!
We re-adjusted w/ the lifters pumped up & viola;
ignition!
Maybe something else for you, but that's what we had. Thanks Crane!
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SECOND AMENDMENT: AMERICA'S ORIGINAL HOMELAND SECURITY!