I've run with and without tubes and had different results with different slicks. I run tubes in my Phoenix 28x10.5" as they are more stable on the top end and consistent (stiffer) off the line. Seems to depend on the tire and the car - no one answer. My Firebird weighs in at 3750lbs with me in it.
My first set of Phoenix slicks leaked air right out the sidewall without tubes...kind of made the decision easy.
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