Since he has the 2262F piston, he has low compression no matter which 6x head he has. I have a 246/253 at 050 cam in one of my 455`s on 108. It`s a rough idling SOB on 462 cubes with 6x#4`s ported to mid 260`s. Pulls 6 to 7 pounds of vac. Runs like a bitch when you mash it though.
I had that cam when I had 62`s on it with 11 to 1 compress. Not a bad cam at that level. Got tired of buying 100 octane gas. Roughly 225 psi cranking pressure with the 62`s and 170 with the 6x.
That 400, with that cam and those heads is gonna be even worse than mine.
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