Charlie do a search on Yellow Bullet... maximum compression E85 in both the NA and turbo sections. See what the extremes are. I think you'll be surprised. I DONT advocate trying the extremes but I'd consider something between the minimums and extremes and adjust accordingly.
BTW inlet temps shouldnt change from compression but turbine may behave differently. (Compression affects EGT). HEAT of COMPRESSED air/fuel will increase!
That said Id keep manifold inlet temps cool(close to ambient) if boosted(A/W intercooler) With compression up where you're at I'd add water injection to slow combustion rate some.
Bigger concern is keeping cylinders sealed and stock block alive.
With your present boost success with E85 on your 4 cylinder you might want to consider staying NA on the 461 and upping compression 2-3 points.
Continue doing your homework!
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